Description

2,5-Bis(Trifluoromethyl)Benzyl Amine is a high-value, fluorinated aromatic amine building block. This compound is prized for its ability to impart unique electronic and lipophilic properties to advanced molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. Its structural features make it a critical intermediate in medicinal chemistry and materials science applications.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and charge-injection layers in organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Catalyst Ligand Precursor: Used to synthesize novel ligands for transition metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Fluorinated Dye & Pigment Intermediate: Employed in the production of high-performance, light-fast dyes and pigments for specialized applications.

Basic Information

Product Name	2,5-Bis(Trifluoromethyl)Benzyl Amine
CAS No.	771582-21-9
Molecular Formula	C10H7F6N
Molecular Weight	255.16 g/mol
Synonyms	[2,5-Bis(trifluoromethyl)phenyl]methanamine; 1-[Aminomethyl]-2,5-bis(trifluoromethyl)benzene; 2,5-Bis(trifluoromethyl)benzylamine; α-Amino-2,5-bis(trifluoromethyl)toluene; (2,5-Bis(trifluoromethyl)benzyl)amine; 2,5-Bis(trifluoromethyl)benzenemethanamine; 771582-21-9; Benzylamine, 2,5-bis(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,5-Bis(Trifluoromethyl)Benzyl Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.