Description

4-Methyl-3-(trifluoromethyl)benzylamine is a versatile aromatic amine building block characterized by its benzylamine core substituted with a methyl and a trifluoromethyl group. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic research.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Methyl-3-(trifluoromethyl)benzylamine
CAS No.	771581-64-7
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	α-Methyl-3-(trifluoromethyl)benzenemethanamine; (4-Methyl-3-(trifluoromethyl)phenyl)methanamine; 3-Trifluoromethyl-4-methylbenzylamine; 1-[4-Methyl-3-(trifluoromethyl)phenyl]methanamine; Benzenemethanamine, 4-methyl-3-(trifluoromethyl)-; 4-Methyl-3-trifluoromethylbenzylamine
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(trifluoromethyl)benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.