Description

7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine Sulphate is a high-purity, specialized heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research and targeted cancer therapies. It is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Biochemical Research: Used as a core scaffold for developing chemical probes and inhibitors in signal transduction pathway studies.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic systems for medicinal chemistry and material science applications.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and drug discovery services.
• Academic Research: Utilized in university and institutional labs for pioneering research in medicinal and synthetic organic chemistry.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine Sulphate
CAS No.	769951-32-8
Molecular Formula	C6H7N5 • H2SO4 (or C6H9N5O4S)
Molecular Weight	263.24 g/mol (for C6H9N5O4S)
Synonyms	4-Amino-7H-pyrrolo[2,3-d]pyrimidine sulfate; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, sulfate (1:1); 4-Amino-7-azaindole sulfate; Pyrrolopyrimidine-4-amine sulfate; 4-Amino-7H-pyrrolo[2,3-d]pyrimidine hemisulfate; 7-Aza-4-aminopyrrolopyrimidine sulfate; 4-Amino-7H-pyrrolo[2,3-d]pyrimidine sulphuric acid salt
EINECS	Contact for details

Quality Control

Our 7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine Sulphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.