Description

6,7-Difluoroquinazoline-2,4(1H,3H)-Dione is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other small-molecule drug candidates.
• Agrochemical Research: Building block for developing new herbicides and fungicides with enhanced activity and selectivity.
• Material Science: Used in the research of organic electronic materials and advanced polymers.
• Chemical Synthesis: Versatile scaffold for medicinal chemistry and the creation of novel heterocyclic libraries for high-throughput screening.
• Academic & R&D: Fundamental reagent for studying structure-activity relationships (SAR) and reaction mechanisms in fluorinated quinazoline chemistry.

Basic Information

Product Name	6,7-Difluoroquinazoline-2,4(1H,3H)-Dione
CAS No.	769158-54-5
Molecular Formula	C8H4F2N2O2
Molecular Weight	198.13 g/mol
Synonyms	6,7-Difluoro-1H,3H-quinazoline-2,4-dione; 6,7-Difluoro-2,4-dihydroxyquinazoline; 6,7-Difluoroquinazoline-2,4-diol; 2,4-Dihydroxy-6,7-difluoroquinazoline; 6,7-Difluoro-2,4(1H,3H)-quinazolinedione; 1H-Quinazoline-2,4-dione, 6,7-difluoro-; 6,7-Difluoro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline
EINECS	Contact for details

Quality Control

Our 6,7-Difluoroquinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.