Description

Pyrido[3,4-D]Pyrimidine-2,4(1H,3H)-Dione, 6-Methoxy- (9Ci) is a high-value heterocyclic organic compound that serves as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique pyrido-pyrimidine-dione scaffold is essential for constructing molecules with targeted biological activity, making it a key building block for medicinal chemists. This compound is primarily utilized in the synthesis of novel drug candidates, particularly within oncology and central nervous system (CNS) therapeutic areas, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Oncology Research: Used as a core scaffold for developing kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Employed in building compounds for neurological and psychiatric disorder research.
• Chemical Biology: Serves as a probe or ligand in studying enzyme function and protein interactions.
• Agrochemical Development: Potential intermediate for creating novel crop protection agents with specific modes of action.
• Academic & Contract Research: Supplied to universities and CROs for fundamental heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Pyrido[3,4-D]Pyrimidine-2,4(1H,3H)-Dione, 6-Methoxy- (9Ci)
CAS No.	769158-28-3
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	6-Methoxypyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione; 6-Methoxy-1H,3H-pyrido[3,4-d]pyrimidine-2,4-dione; 6-Methoxy-1,3-dihydropyrido[3,4-d]pyrimidine-2,4-dione; 6-Methoxy-pyrido[3,4-d]pyrimidine-2,4-diol (tautomer); 769158-28-3; Light-sensitive (store away from light)
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-D]Pyrimidine-2,4(1H,3H)-Dione, 6-Methoxy- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.