Description

3-(2-Fluorobenzyl)Pyrrolidine is a high-purity, fluorinated pyrrolidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a pyrrolidine scaffold with a fluorinated benzyl group, enabling precise modulation of biological activity and physicochemical properties. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor or a functional component in chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagging reagent for studying protein-ligand interactions and enzyme mechanisms.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with tailored properties.

Basic Information

Product Name	3-(2-Fluorobenzyl)Pyrrolidine
CAS No.	768341-24-8
Molecular Formula	C₁₁H₁₄FN
Molecular Weight	179.24 g/mol
Synonyms	3-[(2-Fluorophenyl)methyl]pyrrolidine; 2-Fluorobenzylpyrrolidine; Pyrrolidine, 3-[(2-fluorophenyl)methyl]-; 3-(2-Fluorobenzyl)pyrrolidine; 768341-24-8; 3-(2-Fluorobenzyl)-pyrrolidine; 3-(2-Fluorobenzyl)pyrrolidine hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Fluorobenzyl)Pyrrolidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.