Description

Benzeneethanamine, Beta,3-Difluoro- (9Ci) is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is crucial for modulating biological activity, metabolic stability, and lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the difluoro motif can enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs) due to its aromatic amine functionality.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers, dyes, and liquid crystals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Benzeneethanamine, Beta,3-Difluoro- (9Ci)
CAS No.	767244-83-7
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	2-(3,4-Difluorophenyl)ethanamine; 3,4-Difluorophenethylamine; 2-(3,4-Difluorophenyl)ethylamine; 3,4-Difluorophenylethylamine; β,3-Difluorobenzeneethanamine; (3,4-Difluorophenyl)ethanamine; 767244-83-7 (CAS); 2-(3,4-Difluorophenyl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our Benzeneethanamine, Beta,3-Difluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its amine nature and potential light sensitivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.