Description

1,3,5-Tri-o-Acetyl-2-[2-Oxo-4-(Trimethylsilanyl-Amino)-2H-[1,3,5] Triazin-1-Yl]-β-D-Ribofuranose CAS NO 766536-90-7 is a sophisticated, protected nucleoside derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in enabling the precise construction of modified oligonucleotides and nucleoside analogs, which are essential for pharmaceutical research and development. This high-purity intermediate is specifically designed for use by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical sectors, where it facilitates the creation of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used for the site-specific incorporation of modified bases into DNA and RNA strands for therapeutic and diagnostic applications.
• Prodrug Development: Serves as a protected form in the design and synthesis of prodrugs to enhance bioavailability and targeting.
• Chemical Biology Research: Employed as a tool compound for studying nucleic acid interactions and enzyme mechanisms.
• Agrochemical Research: Utilized in the development of novel pesticides and herbicides that target specific biological pathways.
• Process Chemistry: Acts as a standardized, high-quality starting material for scaling up synthetic routes under GMP conditions.

Basic Information

Item	Details
Product Name	1,3,5-Tri-o-Acetyl-2-[2-Oxo-4-(Trimethylsilanyl-Amino)-2H-[1,3,5] Triazin-1-Yl]-β-D-Ribofuranose
CAS No.	766536-90-7
Molecular Formula	C19H28N4O8Si
Molecular Weight	468.54 g/mol
Synonyms	2-[2-Oxo-4-(Trimethylsilylamino)-1,3,5-triazin-1-yl]-1,3,5-tri-O-acetyl-β-D-ribofuranose; 1,3,5-Tri-O-acetyl-2-[2-oxo-4-(trimethylsilylamino)-2H-1,3,5-triazin-1-yl]-β-D-ribofuranose; Silylated Triazine Ribofuranose Derivative; Protected Ribofuranose Triazine; TAS-Ribofuranose Intermediate
EINECS	Contact for details

Quality Control

Our production of 1,3,5-Tri-o-Acetyl-2-[2-Oxo-4-(Trimethylsilanyl-Amino)-2H-[1,3,5] Triazin-1-Yl]-β-D-Ribofuranose adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.