Description

Ethyl 1-(Chlorosulfonyl)Piperidine-3-Carboxylate (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its reactive chlorosulfonyl group and ester functionality. This compound is critical for medicinal chemists and process development scientists seeking to introduce sulfonamide or sulfonyl chloride motifs into complex molecular architectures. It is primarily utilized in the research and development of novel active pharmaceutical ingredients (APIs), particularly within the fields of oncology, neurology, and anti-infective therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates and other bioactive molecules.
• Medicinal Chemistry R&D: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry: Serves as a versatile reagent in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Agrochemical Research: Potential intermediate in the development of new herbicides or fungicides with novel modes of action.
• Chemical Biology Probes: Can be used to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Ethyl 1-(Chlorosulfonyl)Piperidine-3-Carboxylate (Saltdata: Free)
CAS No.	765962-70-7
Molecular Formula	C8H14ClNO4S
Molecular Weight	255.72 g/mol
Synonyms	1-(Chlorosulfonyl)-3-piperidinecarboxylic acid ethyl ester; Ethyl 1-(chlorosulfonyl)piperidine-3-carboxylate; Ethyl 1-chlorosulfonylpiperidine-3-carboxylate; 3-Piperidinecarboxylic acid, 1-(chlorosulfonyl)-, ethyl ester; 1-Chlorosulfonylpiperidine-3-carboxylic acid ethyl ester; Ethyl 1-(chlorosulfonyl)-3-piperidinecarboxylate; 765962-70-7; 1-(Chlorosulfonyl)piperidine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 1-(Chlorosulfonyl)Piperidine-3-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are manufactured under cGMP-compliant conditions where applicable and are supported by comprehensive analytical data. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.