Description

Ethyl 7-(3-Nitrophenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity, functionalized heterocyclic compound serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that leverage the pyrazolopyrimidine scaffold.
• Material Science Precursor: Serves as a starting material for creating organic electronic materials or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probe Development: Utilized in constructing molecular probes for studying enzyme function and cellular signaling pathways.
• Academic & Contract Research: Essential for methodological research in organic synthesis and heterocyclic chemistry at universities and CROs.
• Scale-up & Process Chemistry: Employed in optimizing synthetic routes from milligram to kilogram scale for commercial production.

Basic Information

Product Name	Ethyl 7-(3-Nitrophenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	765292-65-7
Molecular Formula	C15H12N4O4
Molecular Weight	312.28 g/mol
Synonyms	Ethyl 7-(3-nitrophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 7-(3-Nitrophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(3-nitrophenyl)-, ethyl ester; Ethyl 7-(m-nitrophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; CAS 765292-65-7
EINECS	Contact for details

Quality Control

Our Ethyl 7-(3-Nitrophenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.