Description

Calcitonin (9-32) (Free Acid) (Human) CAS NO 762263-16-1 is a specific, truncated fragment of the human calcitonin hormone, corresponding to amino acid residues 9 through 32 in its free acid form. This peptide is a critical research-grade biochemical tool for studying calcitonin receptor interactions, signal transduction pathways, and structure-activity relationships. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on metabolic bone disease research, peptide drug discovery, and analytical method development.

Application

• Biochemical Research: Used as a reference standard and active ligand in studies of calcitonin receptor binding affinity and selectivity.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and development of novel peptide-based therapeutics for osteoporosis and Paget's disease.
• Structure-Activity Relationship (SAR) Studies: Essential for investigating the biological activity of specific regions of the full-length calcitonin hormone to design optimized analogs.
• Analytical Method Development: Employed as a high-purity standard for calibrating HPLC, LC-MS, and other chromatographic systems in quality control and research laboratories.
• Cell-Based Assays: Used to stimulate cellular responses in vitro to study downstream signaling cascades and metabolic effects related to calcium homeostasis.

Basic Information

Product Name	Calcitonin (9-32) (Free Acid) (Human)
CAS No.	762263-16-1
Molecular Formula	C115H183N35O39S2
Molecular Weight	2635.1 g/mol
Synonyms	Human Calcitonin (9-32) Free Acid; hCT (9-32); Calcitonin Gene-Related Peptide Fragment; CGRP-related peptide; Calcitonin fragment 9-32; H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bridge: Cys1-Cys7) (Free Acid Form); (Disulfide bridge: 1-7)-Human Calcitonin (9-32)
EINECS	Contact for details

Quality Control

Our Calcitonin (9-32) (Free Acid) (Human) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.