Description

Benzenesulfonamide, 2-[(2,5-Dichloro-4-Pyrimidinyl)Amino]-n-Methyl- CAS NO 761440-11-3 is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzenesulfonamide and dichloropyrimidine structure. This compound is critical for the synthesis of targeted small molecule therapeutics, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily utilized by the pharmaceutical and biotechnology industries for the research and production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small molecule drugs, particularly kinase inhibitors.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step manufacturing process of final drug substances.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific biological pathways and targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmaceutical science projects.

Basic Information

Product Name	Benzenesulfonamide, 2-[(2,5-Dichloro-4-Pyrimidinyl)Amino]-n-Methyl-
CAS No.	761440-11-3
Molecular Formula	C11H9Cl2N5O2S
Molecular Weight	346.19 g/mol
Synonyms	N-Methyl-2-[(2,5-dichloro-4-pyrimidinyl)amino]benzenesulfonamide; 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide; 761440-11-3; Benzenesulfonamide, N-methyl-2-[(2,5-dichloro-4-pyrimidinyl)amino]-; 2-[(2,5-Dichloro-pyrimidin-4-yl)amino]-N-methyl-benzenesulfonamide
EINECS	Contact for details

Quality Control

Our Benzenesulfonamide, 2-[(2,5-Dichloro-4-Pyrimidinyl)Amino]-n-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.