Description

D-Leucine, 3-Hydroxy-, Methyl Ester, (3S)-Rel- (9Ci) is a specialized chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. This compound is valued for its role in constructing complex peptide mimetics and other bioactive molecules with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, agrochemicals, and high-value fine chemicals.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of peptide-based drugs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used in medicinal chemistry to create stable analogs of natural peptides for drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Material Science: Potential monomer for creating novel biodegradable polymers or functionalized surfaces with specific chiral properties.

Basic Information

Product Name	D-Leucine, 3-Hydroxy-, Methyl Ester, (3S)-Rel- (9Ci)
CAS No.	761344-55-2
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	(3S)-3-Hydroxy-D-leucine methyl ester; Methyl (3S)-3-hydroxy-D-leucinate; D-3-Hydroxyleucine methyl ester; (R)-2-Amino-4-methyl-3-hydroxy-pentanoic acid methyl ester; Methyl (2R,3S)-2-amino-3-hydroxy-4-methylpentanoate; (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid methyl ester; Rel-(3S)-D-Leucine, 3-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our production of D-Leucine, 3-Hydroxy-, Methyl Ester, (3S)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.