Description

5-Pyrimidinecarboxylic Acid, 1,4-Dihydro-4-Hydroxy-, Methyl Ester (9Ci) is a high-purity heterocyclic building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific pyrimidine-based structures.
• Fine Chemical Building Block: Serves as a versatile precursor in custom synthesis and the manufacture of specialty chemicals, dyes, and complex ligands.
• Academic & Industrial Research: Employed in chemical biology and material science research for studying enzyme inhibition, molecular recognition, and creating new polymeric materials.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	5-Pyrimidinecarboxylic Acid, 1,4-Dihydro-4-Hydroxy-, Methyl Ester (9Ci)
CAS No.	758641-87-1
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	4-Hydroxy-1,4-dihydro-5-pyrimidinecarboxylic acid methyl ester; Methyl 4-hydroxy-1,4-dihydro-5-pyrimidinecarboxylate; 4-Hydroxy-1,4-dihydropyrimidine-5-carboxylic acid methyl ester; 1,4-Dihydro-4-hydroxy-5-pyrimidinecarboxylic acid methyl ester; 5-Carbomethoxy-4-hydroxy-1,4-dihydropyrimidine; Methyl 4-hydroxydihydropyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylic Acid, 1,4-Dihydro-4-Hydroxy-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.