Description

Norleucine, n-Acetyl-4-Methyl- is a chemically modified amino acid derivative, specifically an N-acetylated form of 4-methylnorleucine. This compound is valued for its role as a specialized building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, biochemical studies, and the synthesis of novel peptide-based compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in metabolic pathway studies and as a non-natural amino acid analog to probe enzyme specificity and function.
• Peptide Synthesis: Incorporated into custom peptide sequences to alter physical properties, stability, or biological activity.
• Proteomics & Mass Spectrometry: Can be employed as an internal standard or a labeled analog in quantitative proteomic analyses.
• Chemical Biology: Acts as a tool compound for studying amino acid transport and incorporation mechanisms in biological systems.
• Material Science: Potential use in the development of bio-inspired polymers and functionalized surfaces.

Basic Information

Product Name	Norleucine, n-Acetyl-4-Methyl-
CAS No.	757959-97-0
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	N-Acetyl-4-methylnorleucine; N-Acetyl-4-methyl-2-aminohexanoic acid; 2-Acetamido-4-methylhexanoic acid; (RS)-2-Acetamido-4-methylhexanoic acid; 4-Methyl-N-acetylnorleucine; DL-N-Acetyl-4-methylnorleucine; Ac-4-MeNle-OH
EINECS	Contact for details

Quality Control

Our Norleucine, n-Acetyl-4-Methyl- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, chiral analysis, and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.