Description

2H-Pyrimido[4,5-E]-1,2,4-Thiadiazin-8-Amine,3-Ethyl-3,4-Dihydro-,1,1-Dioxide(9Ci) is a high-purity, complex heterocyclic compound featuring a fused pyrimido-thiadiazine dioxide core structure. This specialized chemical serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research, enabling the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science sectors for targeted synthesis programs.

Application

This compound is designed for advanced research and development applications where its unique molecular architecture is leveraged. Key application scenarios include:

• Pharmaceutical Intermediate: Serving as a key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) or metabolic disorder targets.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop new chemical entities.
• Biochemical Research: Potential use as a tool compound or probe for studying specific enzyme interactions or biological pathways.
• Agrochemical Research: Exploration as an intermediate for novel active ingredients in crop protection products.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations conducting custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2H-Pyrimido[4,5-E]-1,2,4-Thiadiazin-8-Amine,3-Ethyl-3,4-Dihydro-,1,1-Dioxide(9Ci)
CAS No.	757880-57-2
Molecular Formula	C7H9N5O2S
Molecular Weight	227.25 g/mol
Synonyms	3-Ethyl-3,4-dihydro-2H-pyrimido[4,5-e][1,2,4]thiadiazin-8-amine 1,1-dioxide; 757880-57-2; 2H-Pyrimido[4,5-e]-1,2,4-thiadiazin-8-amine, 3-ethyl-3,4-dihydro-, 1,1-dioxide; 3-Ethyl-3,4-dihydro-2H-[1,2,4]thiadiazino[5,6-e]pyrimidin-8-amine 1,1-dioxide; Pyrimido-thiadiazine dioxide derivative; 3-Ethyl-dihydro-pyrimidothiadiazinamine dioxide.
EINECS	Contact for details

Quality Control

Our high-purity research-grade products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent specifications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by advanced analytical techniques including HPLC, NMR, and MS. We adhere to a cGMP-compliant quality management system for traceability and documentation, ensuring reliability for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.