Description

4-Amino-2-Chloro-3-Fluorobenzaldehyde is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, chloro, and fluoro substituents on a benzaldehyde core, makes it a high-value intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce specific halogenated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzaldehyde scaffold.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and pigments, where its functional groups allow for further chemical modification.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecular targets.

Basic Information

Product Name	4-Amino-2-Chloro-3-Fluorobenzaldehyde
CAS No.	757247-98-6
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Chloro-3-fluoro-4-aminobenzaldehyde; 3-Fluoro-2-chloro-4-aminobenzaldehyde; 4-Amino-2-chloro-3-fluorobenzaldehyde; Benzaldehyde, 4-amino-2-chloro-3-fluoro-; 2-Chloro-3-fluoro-4-formylaniline; 4-Amino-2-chloro-3-fluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloro-3-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), impurity profiles, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.