Description

(3-Bromophenyl)(4,6-Dichloropyrimidin-5-Yl)Methanone is a high-purity, synthetically valuable heterocyclic building block characterized by its bromophenyl and dichloropyrimidine functional groups. This compound is essential for advanced organic synthesis, serving as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• Material Science: Serves as a building block for organic electronic materials and liquid crystals due to its rigid, aromatic structure.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: A valuable reagent for methodological studies in cross-coupling reactions and heterocyclic chemistry at universities and research institutes.

Basic Information

Product Name	(3-Bromophenyl)(4,6-Dichloropyrimidin-5-Yl)Methanone
CAS No.	754190-28-8
Molecular Formula	C11H5BrCl2N2O
Molecular Weight	332.98 g/mol
Synonyms	5-(3-Bromobenzoyl)-4,6-dichloropyrimidine; (3-Bromobenzoyl)-4,6-dichloropyrimidine; 4,6-Dichloro-5-(3-bromobenzoyl)pyrimidine; Methanone, (3-bromophenyl)(4,6-dichloro-5-pyrimidinyl)-; 754190-28-8; AKOS005258213
EINECS	Contact for details

Quality Control

Every batch of (3-Bromophenyl)(4,6-Dichloropyrimidin-5-Yl)Methanone is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.