Description

Benzenecarboximidamide, 3-Fluoro-4-Hydroxy- (9Ci) is a fluorinated hydroxybenzamidine derivative, a key chemical intermediate prized for its unique structural motif. This compound matters for its role in synthesizing more complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the amidine and phenolic groups are essential for binding.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its fluorine atom for metabolic stability and bioavailability.
• Chemical Synthesis Reagent: Acts as a versatile precursor for constructing heterocyclic compounds, such as imidazoles and benzimidazoles, which are prevalent in medicinal chemistry.
• Ligand and Chelator Development: The amidine and phenolic hydroxyl groups make it a candidate for developing metal-chelating ligands used in catalysis or analytical chemistry.
• Bioconjugation and Probe Synthesis: Utilized in life sciences research for creating fluorescent probes or affinity tags due to its modifiable functional groups.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials where fluorinated aromatic units are required.

Basic Information

Product Name	Benzenecarboximidamide, 3-Fluoro-4-Hydroxy- (9Ci)
CAS No.	752190-40-2
Molecular Formula	C7H7FN2O
Molecular Weight	154.14 g/mol
Synonyms	3-Fluoro-4-hydroxybenzamidine; 4-Hydroxy-3-fluorobenzamidine; 3-Fluoro-4-hydroxybenzenecarboximidamide; (3-Fluoro-4-hydroxyphenyl)methanimidamide; 3-Fluoro-4-hydroxybenzene-1-carboximidamide; 3-Fluoro-4-hydroxybenzenecarboximidamide (9CI); 3-Fluoro-4-hydroxybenzamidine hydrochloride (salt form common); 752190-40-2
EINECS	Contact for details

Quality Control

Our Benzenecarboximidamide, 3-Fluoro-4-Hydroxy- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 95.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.