Description

Threo-Hex-4-Enonic Acid, 2-Amino-3,6-Anhydro-2,4,5-Trideoxy-5-Methyl- (9Ci) is a specialized chiral building block and advanced pharmaceutical intermediate. This compound is valued for its unique stereochemistry and functional groups, which make it a critical precursor in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of antiviral and antibiotic drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially nucleoside analogs.
• Antiviral Drug Research: Serves as a core structural component in the synthesis of potential antiviral agents targeting various viral families.
• Antibiotic Development: Used in the construction of novel sugar-based antibiotic scaffolds to combat drug-resistant bacteria.
• Glycochemistry Research: An important substrate for studying glycosylation reactions and synthesizing complex carbohydrates or glycomimetics.
• Chemical Biology Probes: Utilized in the creation of labeled compounds or probes for investigating biological pathways and enzyme mechanisms.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of target drug candidates.

Basic Information

Product Name	Threo-Hex-4-Enonic Acid, 2-Amino-3,6-Anhydro-2,4,5-Trideoxy-5-Methyl- (9Ci)
CAS No.	750567-18-1
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	2-Amino-3,6-anhydro-2,4,5-trideoxy-5-methyl-D-threo-hex-4-enonic acid; (2R,3R)-2-Amino-3,6-anhydro-2,4,5-trideoxy-5-methyl-4-hexenoic acid; D-threo-Hex-4-enonic acid, 2-amino-3,6-anhydro-2,4,5-trideoxy-5-methyl-; 750567-18-1; UNII-9V6T7QY6IJ; 9V6T7QY6IJ; SCHEMBL2182741; DTXSID701330076
EINECS	Contact for details

Quality Control

Our Threo-Hex-4-Enonic Acid, 2-Amino-3,6-Anhydro-2,4,5-Trideoxy-5-Methyl- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere. The product is hygroscopic and should be handled in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.