Description

2-Amino-4-(4-Bromophenyl)-5-Pyrimidinecarbonitrile is a high-value brominated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a nitrile group, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for creating specialized organic ligands and functionalized polymers.
• Chemical Synthesis: Employed in cross-coupling reactions and cyclization processes to create more complex nitrogen-containing heterocycles.
• Academic & R&D: Utilized in universities and contract research organizations (CROs) for methodological studies and discovery chemistry.

Basic Information

Product Name	2-Amino-4-(4-Bromophenyl)-5-Pyrimidinecarbonitrile
CAS No.	749885-93-6
Molecular Formula	C11H7BrN4
Molecular Weight	275.11 g/mol
Synonyms	4-(4-Bromophenyl)-2-amino-5-pyrimidinecarbonitrile; 2-Amino-4-(p-bromophenyl)-5-cyanopyrimidine; 5-Cyano-2-amino-4-(4-bromophenyl)pyrimidine; 749885-93-6; 2-Amino-4-(4'-bromophenyl)-5-pyrimidinecarbonitrile; 4-(4-Bromophenyl)-2-aminopyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Bromophenyl)-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.