Description

Methanone, [3-[(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)Sulfonyl]Phenyl][4-(2-Pyrimidinyl)-1-Piperazinyl]- is a high-purity, synthetic organic compound featuring a complex molecular architecture combining indoline, sulfonyl, and piperazinyl-pyrimidine motifs. This compound is of significant interest for its potential as a key pharmaceutical intermediate or biological research probe, particularly in the development of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for targeted synthesis programs.

Application

This specialized chemical serves as a critical building block in advanced synthetic chemistry. Its primary applications include:

• Pharmaceutical Intermediate: Used in the research and development of new active pharmaceutical ingredients (APIs), potentially for central nervous system or oncological targets.
• Biochemical Research: Acts as a reference standard or a precursor in the study of enzyme inhibition, receptor binding assays, and other pharmacological studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Item	Details
Product Name	Methanone, [3-[(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)Sulfonyl]Phenyl][4-(2-Pyrimidinyl)-1-Piperazinyl]-
CAS No.	749868-66-4
Molecular Formula	C24H25N5O3S
Molecular Weight	463.55 g/mol
Synonyms	1-[3-[[(2-Methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl]carbonyl]-4-(pyrimidin-2-yl)piperazine; [3-[(2-Methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl]-[4-(pyrimidin-2-yl)piperazin-1-yl]methanone; 749868-66-4; UNII-9J8K4A8U6Q; 9J8K4A8U6Q; BDBM50391479; AKOS025310647; ZINC000004169786.
EINECS	Contact for details

Quality Control

Our production of Methanone, [3-[(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)Sulfonyl]Phenyl][4-(2-Pyrimidinyl)-1-Piperazinyl]- adheres to stringent quality protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters are provided and available upon request. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.