Description

2H-Indol-2-One,5-Amino-1-Ethyl-3,3-Difluoro-1,3-Dihydro-(9Ci) is a specialized fluorinated indole derivative, a high-value intermediate prized for its unique molecular scaffold. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where the difluoro and amino groups impart specific biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced efficacy and environmental profile.
• Fluorinated Building Block: Serves as a versatile synthon for introducing the difluoroindole motif into more complex molecules in medicinal and synthetic chemistry.
• Material Science Research: Investigated for potential use in the development of organic electronic materials and specialty dyes due to its conjugated indole structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2H-Indol-2-One,5-Amino-1-Ethyl-3,3-Difluoro-1,3-Dihydro-(9Ci)
CAS No.	748808-09-5
Molecular Formula	C10H10F2N2O
Molecular Weight	212.20 g/mol
Synonyms	5-Amino-1-ethyl-3,3-difluoro-1,3-dihydro-2H-indol-2-one; 5-Amino-1-ethyl-3,3-difluoroindolin-2-one; 1-Ethyl-5-amino-3,3-difluoro-2-indolinone; 748808-09-5; 3,3-Difluoro-5-amino-1-ethyl-2-indolinone; 5-Amino-1-ethyl-3,3-difluoro-2-oxindole; 2H-Indol-2-one, 5-amino-1-ethyl-3,3-difluoro-1,3-dihydro- (9CI)
EINECS	Contact for details

Quality Control

Our 2H-Indol-2-One,5-Amino-1-Ethyl-3,3-Difluoro-1,3-Dihydro-(9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.