Description

Benzenemethanol, 2-Amino-4,5-Difluoro- (9Ci) is a fluorinated aromatic amino alcohol building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• As a versatile pharmaceutical intermediate for the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) agents.
• In agrochemical research for developing novel herbicides, fungicides, and pesticides with enhanced efficacy and environmental profile.
• As a specialized building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• For the synthesis of advanced materials, such as liquid crystals or functional polymers, where fluorinated aromatic units are required.
• In custom synthesis and contract manufacturing for clients requiring specific, high-purity fluorinated intermediates.
• As a reference standard in analytical laboratories for method development and quality control of related compounds.

Basic Information

Product Name	Benzenemethanol, 2-Amino-4,5-Difluoro- (9Ci)
CAS No.	748805-87-0
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	2-Amino-4,5-difluorobenzyl alcohol; (2-Amino-4,5-difluorophenyl)methanol; 4,5-Difluoro-2-aminobenzyl alcohol; 2-(Aminomethyl)-4,5-difluorophenol (tautomer); Benzenemethanol, 2-amino-4,5-difluoro-; 748805-87-0; 2-Amino-4,5-difluoro-benzenemethanol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, 2-Amino-4,5-Difluoro- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and other relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.