Description

L-Asparagine-15N2 is a stable isotope-labeled analog of the amino acid L-asparagine, specifically enriched with two nitrogen-15 atoms. This high-purity labeled compound is essential for advanced research requiring precise metabolic and proteomic pathway tracing. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors for applications in mass spectrometry, NMR spectroscopy, and stable isotope labeling studies.

Application

• Metabolic Pathway Analysis: Used as a tracer in in vivo and in vitro studies to investigate nitrogen metabolism and amino acid biosynthesis.
• Quantitative Proteomics & Mass Spectrometry (MS): Serves as an internal standard for the accurate quantification of asparagine and related metabolites in complex biological samples.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Provides a non-radioactive, highly sensitive probe for structural and dynamic studies of biomolecules.
• Drug Discovery & Development: Employed in pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies of drug candidates.
• Nutritional & Biomedical Research: Facilitates studies on amino acid utilization, cellular signaling, and diseases related to asparagine metabolism.
• Production of Labeled Biomolecules: Acts as a building block for the synthesis of peptides, proteins, and other nitrogen-15 labeled compounds.

Basic Information

Product Name	L-Asparagine-15N2
CAS No.	748757-99-5
Molecular Formula	C4H815N2O3
Molecular Weight	134.09 g/mol (for 15N2 labeled form)
Synonyms	(2S)-2-Amino-3-carbamoylpropanoic-15N2 acid; L-Asparagine (15N2); Asparagine-15N2; (S)-2-Amino-3-carbamoylpropanoic-15N2 acid; Asn-15N2; L-Asn-15N2; Nitrogen-15 labeled L-asparagine; Stable isotope-labeled asparagine
EINECS	Contact for details

Quality Control

Our L-Asparagine-15N2 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to relevant industry standards for stable isotope-labeled compounds, ensuring reliability for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (15N)	≥ 98 atom % 15N
Specific Rotation	+31.5° to +35.0° (c=1 in H2O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.