Description

(R)-3-Amino-3-(3-Methyl-Phenyl)-Propionic Acid is a high-purity, non-natural chiral amino acid derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where precise stereochemistry is essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetics & Drug Discovery: Used to incorporate a constrained, non-proteinogenic amino acid moiety into peptide chains to enhance stability, bioavailability, and receptor selectivity.
• Asymmetric Synthesis: Employed as a chiral pool starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Chemical Biology & Proteomics: Serves as a specialized building block for synthesizing probes, inhibitors, and labeled compounds used in mechanistic and target identification studies.
• Agrochemical Research: Potential intermediate in the synthesis of chiral herbicides, fungicides, or plant growth regulators requiring specific stereochemistry for optimal activity.

Basic Information

Item	Detail
Product Name	(R)-3-Amino-3-(3-Methyl-Phenyl)-Propionic Acid
CAS No.	748128-33-8
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-3-Amino-3-(m-Tolyl)propanoic Acid; (R)-3-Amino-3-(3-Methylphenyl)propanoic Acid; (R)-β-Amino-β-(3-methylphenyl)propionic Acid; (R)-3-(3-Methylphenyl)-3-aminopropanoic Acid; D-3-Amino-3-(3-methylphenyl)propionic Acid; (R)-3-(m-Tolyl)-3-aminopropionic Acid; (R)-m-Methyl-β-phenyl-β-alanine
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(3-Methyl-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.