Description

2-(Trifluoromethyl)Phenylglyoxal Hydrate is a specialized trifluoromethylated α-dicarbonyl compound, serving as a versatile and high-value building block in advanced organic synthesis. Its core value lies in the unique reactivity of the glyoxal moiety combined with the electron-withdrawing and lipophilicity-enhancing properties of the trifluoromethyl group. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorinated motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing fluorinated heterocycles, including imidazoles, quinoxalines, and other nitrogen-containing bioactive compounds.
• Agrochemical Synthesis: Building block for developing novel pesticides and herbicides where the CF₃ group improves biological activity and environmental stability.
• Material Science Research: Used in the preparation of fluorinated organic ligands, polymers, and advanced functional materials.
• Chemical Biology Probes: Serves as a reactive handle for bioconjugation and the development of fluorinated probes and inhibitors.
• Cross-Coupling & Condensation Reactions: Employed in reactions with diamines, hydrazines, and other nucleophiles to construct complex molecular frameworks.

Basic Information

Product Name	2-(Trifluoromethyl)Phenylglyoxal Hydrate
CAS No.	745783-91-9
Molecular Formula	C₉H₅F₃O₃
Molecular Weight	218.13 g/mol
Synonyms	2-(Trifluoromethyl)benzoylformaldehyde hydrate; 2-(Trifluoromethyl)phenylethanedione hydrate; α-Oxo-2-(trifluoromethyl)benzeneacetaldehyde hydrate; (2-Trifluoromethylphenyl)glyoxal hydrate; 2-(Trifluoromethyl)phenyl-1,2-diketoethane hydrate
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Phenylglyoxal Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.