Description

6-(4-Fluorophenyl)Furo[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the furopyrimidine class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. This compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation small molecule drugs. The structural motif of the furopyrimidine scaffold is prized for its ability to modulate key biological pathways.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of novel kinase inhibitors and other targeted cancer therapies.
• Antiviral Drug Research: Key precursor in the development of compounds targeting viral replication enzymes.
• Biochemical Research: Used as a reference standard and probe molecule in enzymatic and receptor binding studies.
• Organic Synthesis: Serves as a versatile scaffold for medicinal chemistry optimization and structure-activity relationship (SAR) studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	6-(4-Fluorophenyl)Furo[2,3-D]Pyrimidin-4-Amine
CAS No.	744255-26-3
Molecular Formula	C₁₂H₈FN₃O
Molecular Weight	229.21 g/mol
Synonyms	6-(4-Fluorophenyl)furo[2,3-d]pyrimidin-4-amine; 4-Amino-6-(4-fluorophenyl)furo[2,3-d]pyrimidine; Furo[2,3-d]pyrimidin-4-amine, 6-(4-fluorophenyl)-; 744255-26-3; 6-(p-Fluorophenyl)furo[2,3-d]pyrimidin-4-ylamine; 6-(4-Fluorophenyl)-4-aminofuro[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)Furo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment. We support development from research to commercial scale with consistent quality and full regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.