Description

7-Bromo-2-Chloroquinazolin-4(3H)-One is a high-purity, halogenated quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its versatile reactivity, particularly in constructing complex heterocyclic scaffolds for pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core structure.
• Chemical Synthesis Building Block: Serves as a versatile substrate for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions.
• Material Science Research: Potential intermediate for the development of organic electronic materials and photoactive compounds.
• Academic & Contract Research: Essential for medicinal chemistry programs and exploratory research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	7-Bromo-2-Chloroquinazolin-4(3H)-One
CAS No.	744229-27-4
Molecular Formula	C8H4BrClN2O
Molecular Weight	259.49 g/mol
Synonyms	7-Bromo-2-chloro-3,4-dihydroquinazolin-4-one; 2-Chloro-7-bromoquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 7-bromo-2-chloro-; 7-Bromo-2-chloro-4-hydroxyquinazoline; 7-Bromo-2-chloroquinazolin-4-ol
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Chloroquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.