Description

4-Pyrimidinecarboxylicacid,2-(Aminomethyl)-1,4,5,6-Tetrahydro-(9Ci) is a specialized heterocyclic building block featuring both a carboxylic acid and an aminomethyl functional group on a partially saturated pyrimidine core. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, particularly for creating novel drug candidates targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in neurological and psychiatric drug discovery.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via parallel synthesis and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled compounds or probes to study biological pathways and enzyme functions.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel herbicides or plant growth regulators.
• Material Science: Can be utilized in the synthesis of specialty polymers or ligands for metal-organic frameworks (MOFs) due to its chelating potential.

Basic Information

Product Name	4-Pyrimidinecarboxylicacid,2-(Aminomethyl)-1,4,5,6-Tetrahydro-(9Ci)
CAS No.	744175-78-8
Molecular Formula	C7H11N3O2
Molecular Weight	169.18 g/mol
Synonyms	2-(Aminomethyl)-1,4,5,6-tetrahydro-4-pyrimidinecarboxylic acid; 1,4,5,6-Tetrahydro-2-(aminomethyl)pyrimidine-4-carboxylic acid; 2-(Aminomethyl)-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 2-(aminomethyl)-1,4,5,6-tetrahydro-; 744175-78-8; 2-Aminomethyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinecarboxylicacid,2-(Aminomethyl)-1,4,5,6-Tetrahydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.