Description

2-(1-Pyrrolidinylmethyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is essential for research and development chemists, process scale-up teams, and manufacturers in the global pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a standardized building block for kilogram-to-ton scale API manufacturing under GMP conditions.
• Biochemical Tool Compound: Potential use in biochemical assays and as a pharmacological probe for target validation in academic and industrial research.
• Custom Synthesis: Basis for the custom manufacturing of complex molecules and derivatives for client-specific drug discovery programs.

Basic Information

Product Name	2-(1-Pyrrolidinylmethyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	742094-61-7
Molecular Formula	C₁₇H₂₁N₃OS
Molecular Weight	315.43 g/mol
Synonyms	2-[(Pyrrolidin-1-yl)methyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 2-(Pyrrolidin-1-ylmethyl)-4-oxo-3,4,5,6,7,8-hexahydro-1-benzothieno[2,3-d]pyrimidine; THTP-Pyrrolidinylmethyl derivative; CAS 742094-61-7; Benzothienopyrimidinone derivative; Fused tetracyclic pyrrolidinyl pyrimidinone
EINECS	Contact for details

Quality Control

Our production of 2-(1-Pyrrolidinylmethyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One adheres to stringent quality management systems. Every batch is analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. We support development and commercial projects requiring ICH stability data and can supply material manufactured under cGMP guidelines for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.