Description

2-Trifluoromethyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a tetrahydropyridopyrimidine scaffold with a strategically positioned trifluoromethyl group, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the creation of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity-enhancing properties of the trifluoromethyl group.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for advanced organic materials, such as ligands for catalysis or components in specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and development projects.

Basic Information

Product Name	2-Trifluoromethyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine
CAS No.	741737-16-6
Molecular Formula	C9H8F3N3
Molecular Weight	215.18 g/mol
Synonyms	5,6,7,8-Tetrahydro-2-(trifluoromethyl)pyrido[4,3-d]pyrimidine; 2-(Trifluoromethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 741737-16-6; Pyrido[4,3-d]pyrimidine, 5,6,7,8-tetrahydro-2-(trifluoromethyl)-; 2-Trifluoromethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC), identity confirmation (by NMR/IR), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.