Description

Methanone, [4-Amino-2-(Ethylthio)-5-Pyrimidinyl](2,3-Difluoro-6-Methoxyphenyl)- is a high-purity, specialized organic compound featuring a unique pyrimidine-based structure with fluorine and sulfur substituents. This compound is a critical advanced pharmaceutical intermediate (API intermediate) valued for its role in synthesizing novel active ingredients. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and oncology research pipelines.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including ligands for catalysis and organic electronic components.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry studies and structure-activity relationship (SAR) exploration.
• Fine Chemical Synthesis: Utilized in custom synthesis and process development for high-value, low-volume specialty chemicals.

Basic Information

Product Name	Methanone, [4-Amino-2-(Ethylthio)-5-Pyrimidinyl](2,3-Difluoro-6-Methoxyphenyl)-
CAS No.	741713-37-1
Molecular Formula	C14H13F2N3O2S
Molecular Weight	325.33 g/mol
Synonyms	(2,3-Difluoro-6-methoxyphenyl)[4-amino-2-(ethylsulfanyl)-5-pyrimidinyl]methanone; 4-Amino-2-(ethylthio)-5-pyrimidinyl(2,3-difluoro-6-methoxyphenyl)methanone; 741713-37-1; CAS 741713-37-1; 2,3-Difluoro-6-methoxybenzoyl-4-amino-2-ethylthiopyrimidine; Pyrimidine Methanone Derivative; API Intermediate 741713-37-1
EINECS	Contact for details

Quality Control

Our production of Methanone, [4-Amino-2-(Ethylthio)-5-Pyrimidinyl](2,3-Difluoro-6-Methoxyphenyl)- adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. All batches undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and compliance. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.