Description

Ethyl 7-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in modern pharmaceutical synthesis. This compound matters because it provides a versatile and structurally defined scaffold for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D departments and fine chemical manufacturers need this material for its role in constructing pyrazolopyrimidine-based molecules, which are prominent in medicinal chemistry for their diverse biological activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the pyrazolopyrimidine core.
• Chemical Biology & Proteomics: Employed as a molecular probe or scaffold in the design of chemical tools for studying biological pathways.
• Academic & Contract Research: Serves as a starting material for methodological development and novel heterocyclic chemistry in university and CRO laboratories.
• Material Science Precursor: Investigated for the synthesis of organic electronic materials due to its conjugated aromatic system.

Basic Information

Product Name	Ethyl 7-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	741710-05-4
Molecular Formula	C15H12ClN3O2
Molecular Weight	301.73 g/mol
Synonyms	Ethyl 7-(p-chlorophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 7-(4-Chlorophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; 741710-05-4; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(4-chlorophenyl)-, ethyl ester; Ethyl 7-(4-chlorophenyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 7-(4-Chlorophenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.