Description

Imidazo[1,2-C]Pyrimidin-5(1H)-One, 8-Fluoro-2,3-Dihydro- (9Ci) is a high-value fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical and agrochemical agents, where its unique fused ring system and fluorine substituent impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers with specialized properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Imidazo[1,2-C]Pyrimidin-5(1H)-One, 8-Fluoro-2,3-Dihydro- (9Ci)
CAS No.	740736-64-5
Molecular Formula	C6H4FN3O
Molecular Weight	153.11 g/mol
Synonyms	8-Fluoro-2,3-dihydro-1H-imidazo[1,2-c]pyrimidin-5-one; 8-Fluoro-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-5-one; 8-Fluoro-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one; 740736-64-5; Imidazo[1,2-c]pyrimidin-5(1H)-one, 8-fluoro-2,3-dihydro-; 8-Fluoro-1,5-dihydroimidazo[1,2-c]pyrimidin-5-one; 8-Fluoro-2,3-dihydro-1H-imidazo[1,2-c]pyrimidin-5-one
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-C]Pyrimidin-5(1H)-One, 8-Fluoro-2,3-Dihydro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.