Description

2-(Hydroxymethyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. Its core value lies in its bifunctional pyrazolopyrimidine scaffold, which serves as a versatile precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research pipelines.
• Agrochemical Development: Used as a building block for creating new herbicides, fungicides, and plant growth regulators with targeted activity.
• Organic Synthesis & Research: Serves as a versatile precursor in academic and industrial laboratories for constructing complex heterocyclic systems and exploring new chemical spaces.
• Material Science: Potential application in the development of advanced organic electronic materials or metal-organic frameworks (MOFs) due to its functionalized aromatic structure.
• Bioconjugation & Probe Synthesis: The carboxylic acid and hydroxymethyl groups allow for derivatization, making it useful for creating biochemical probes or labeled compounds.

Basic Information

Product Name	2-(Hydroxymethyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid
CAS No.	739365-04-9
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	2-(Hydroxymethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 2-(hydroxymethyl)-; 2-Hydroxymethyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid; 739365-04-9; 2-(Hydroxymethyl)-1H-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid; 2-(Hydroxymethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (ACD/Name 4.0)
EINECS	Contact for details

Quality Control

Our production of 2-(Hydroxymethyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We operate under a quality system designed to meet the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.