Description

Propanamide, n-(5-Bromo-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)-2,2-Dimethyl- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily sought by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Biochemical Research: Used as a reference standard and a core scaffold in structure-activity relationship (SAR) studies.
• Anticancer Agent Development: Serves as a vital structural component in the research and development of potential anticancer therapeutics.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to introduce the functionalized pyrrolopyrimidine moiety.
• Process Chemistry: Utilized in route scouting and scale-up processes for active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	Propanamide, n-(5-Bromo-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)-2,2-Dimethyl-
CAS No.	737792-28-8
Molecular Formula	C11H12BrClN4O
Molecular Weight	331.60 g/mol
Synonyms	2,2-Dimethyl-N-(5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)propanamide; 5-Bromo-4-chloro-2-(2,2-dimethylpropanamido)-7H-pyrrolo[2,3-d]pyrimidine; 737792-28-8; N-(5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-(5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)propionamide
EINECS	Contact for details

Quality Control

Our Propanamide, n-(5-Bromo-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)-2,2-Dimethyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.