Description

Propanamide, n-(4,5-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)-2,2-Dimethyl- is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound serves as a key building block in the synthesis of targeted therapeutic agents, offering researchers precise control over molecular structure and function. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the discovery and development of new anticancer drug candidates due to its pyrrolopyrimidine core, a privileged scaffold in medicinal chemistry.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for creating probes to study specific biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for cutting-edge research in medicinal chemistry and drug design.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	Propanamide, n-(4,5-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)-2,2-Dimethyl-
CAS No.	737792-27-7
Molecular Formula	C11H12Cl2N4O
Molecular Weight	287.15 g/mol
Synonyms	2,2-Dimethyl-N-(4,5-dichloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)propanamide; N-(4,5-Dichloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethylpropanamide; 737792-27-7; 2,2-Dimethylpropionamide, N-(4,5-dichloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-; Propanamide, 2,2-dimethyl-N-(4,5-dichloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-; 4,5-Dichloro-2-(2,2-dimethylpropionamido)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Propanamide, n-(4,5-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)-2,2-Dimethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.