Description

4-Pyrimidinamine, 5-Bromo-n-Cyclopentyl-2-(Methylthio)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active compounds. This brominated, thiomethyl-substituted pyrimidine derivative is a critical building block for medicinal chemistry research and development, offering a unique scaffold for structure-activity relationship (SAR) studies. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for lead optimization and the exploration of new chemical entities (NCEs) in drug discovery programs.
• Agrochemical Development: Acts as a building block for creating novel herbicides, fungicides, or insecticides with targeted modes of action.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Used in university and institutional laboratories for fundamental research in heterocyclic and organosulfur chemistry.

Basic Information

Product Name	4-Pyrimidinamine, 5-Bromo-n-Cyclopentyl-2-(Methylthio)-
CAS No.	733039-23-1
Molecular Formula	C10H14BrN3S
Molecular Weight	288.21 g/mol
Synonyms	5-Bromo-N-cyclopentyl-2-(methylthio)pyrimidin-4-amine; 5-Bromo-2-(methylthio)-N-cyclopentylpyrimidin-4-amine; 5-Bromo-N-cyclopentyl-2-(methylsulfanyl)pyrimidin-4-amine; 4-Amino-5-bromo-2-(methylthio)-N-cyclopentylpyrimidine; 733039-23-1; 5-Bromo-2-methylthio-N-cyclopentylpyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinamine, 5-Bromo-n-Cyclopentyl-2-(Methylthio)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, such as pharmaceutical R&D and GMP (Good Manufacturing Practice) starting material preparation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.