Description

4-Pyrimidinamine, 5-Bromo-n-Cyclopentyl-2-(Methylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated pyrimidine core. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting kinase inhibition. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to develop next-generation therapeutic agents, leveraging its unique structure for creating potent and selective drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitor drugs for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and further functionalization due to the reactive bromine and sulfonyl groups.
• Biochemical Tool Compound: Serves as a reference standard or probe molecule in biochemical assays and target validation studies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized APIs and novel chemical entities (NCEs).
• Agrochemical Research: Potential application in the synthesis of advanced crop protection agents with specific biological activity.

Basic Information

Product Name	4-Pyrimidinamine, 5-Bromo-n-Cyclopentyl-2-(Methylsulfonyl)-
CAS No.	733039-22-0
Molecular Formula	C10H14BrN3O2S
Molecular Weight	320.21 g/mol
Synonyms	5-Bromo-N-cyclopentyl-2-(methylsulfonyl)pyrimidin-4-amine; 5-Bromo-2-(methylsulfonyl)-N-cyclopentylpyrimidin-4-amine; 4-Amino-5-bromo-N-cyclopentyl-2-(methylsulfonyl)pyrimidine; 733039-22-0; 5-Bromo-N-cyclopentyl-2-methanesulfonyl-pyrimidin-4-amine; 5-Bromo-2-(methanesulfonyl)-N-cyclopentyl-4-pyrimidinamine; 4-Pyrimidinamine, 5-bromo-N-cyclopentyl-2-(methylsulfonyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Pyrimidinamine, 5-Bromo-n-Cyclopentyl-2-(Methylsulfonyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development use. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.