Description

2-(1-Chloroethyl)-7-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic class of compounds. Its complex molecular architecture makes it a critical building block for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) disorders. This compound is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality intermediates to accelerate their discovery pipelines and ensure robust manufacturing processes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting, scale-up studies, and the development of Good Manufacturing Practice (GMP) processes for Active Pharmaceutical Ingredients (APIs).
• Oncology Drug Development: Its benzothienopyrimidinone structure is relevant for developing targeted cancer therapies.
• CNS Drug Discovery: Applied in research for neurological and psychiatric disorders due to the pharmacophore's potential CNS activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for chemical biology studies and novel heterocyclic chemistry exploration.

Basic Information

Item	Details
Product Name	2-(1-Chloroethyl)-7-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	733030-56-3
Molecular Formula	C15H17ClN2OS
Molecular Weight	308.82 g/mol
Synonyms	7-Methyl-2-(1-chloroethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 2-(α-Chloroethyl)-7-methyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine; THBTP derivative; Benzothieno[2,3-d]pyrimidin-4-one derivative; CAS 733030-56-3; Fused thienopyrimidinone; Chloroethyl tetrahydrobenzothienopyrimidinone
EINECS	Contact for details

Quality Control

Every batch of 2-(1-Chloroethyl)-7-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments. Certificates of Analysis (COA) are supplied with each shipment, detailing purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods (HPLC, GC, NMR, MS). Our quality commitment ensures batch-to-batch consistency and traceability for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.