Description

4-Chloro-5-(Chloromethyl)-2-Methylpyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its bifunctional reactivity, featuring both a chloro and a chloromethyl group on the pyrimidine core, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with tailored biological activity.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential intermediate in the synthesis of functionalized polymers or organic electronic materials.

Basic Information

Product Name	4-Chloro-5-(Chloromethyl)-2-Methylpyrimidine
CAS No.	731766-78-2
Molecular Formula	C6H6Cl2N2
Molecular Weight	177.03 g/mol
Synonyms	2-Methyl-4-chloro-5-chloromethylpyrimidine; 5-(Chloromethyl)-4-chloro-2-methylpyrimidine; 4-Chloro-2-methyl-5-(chloromethyl)pyrimidine; 2-Methyl-4,5-dichloromethylpyrimidine (incorrect but common); Pyrimidine, 4-chloro-5-(chloromethyl)-2-methyl-; CCMP (abbreviation); CAS 731766-78-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-(Chloromethyl)-2-Methylpyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.