Description

2-(Chloromethyl)-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylic Acid is a high-value, multi-functional heterocyclic building block with significant synthetic utility. This compound is critical for research and development in advanced organic synthesis, particularly in constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of quinazoline-based drug candidates, including potential kinase inhibitors and other therapeutic agents.
• Organic Synthesis Building Block: Used for constructing complex heterocyclic frameworks due to its reactive chloromethyl and carboxylic acid functional groups.
• Agrochemical Research: Serves as a key starting material in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or precursor for the synthesis of specialty polymers and advanced functional materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development studies within university and CRO laboratories.

Basic Information

Product Name	2-(Chloromethyl)-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylic Acid
CAS No.	730976-58-6
Molecular Formula	C10H7ClN2O3
Molecular Weight	238.63 g/mol
Synonyms	7-Quinazolinecarboxylic acid, 2-(chloromethyl)-3,4-dihydro-4-oxo-; 2-(Chloromethyl)-4-oxo-1,4-dihydroquinazoline-7-carboxylic acid; 2-(Chloromethyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid; 730976-58-6; Quinazoline-7-carboxylic acid, 2-(chloromethyl)-4-oxo-3,4-dihydro-; 2-(Chloromethyl)-4-oxoquinazoline-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-(Chloromethyl)-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis work. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, NMR, and mass spectrometry. We operate under a cGMP-compliant mindset suitable for advanced intermediate manufacturing, ensuring traceability and documentation meet the high standards of the pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.