Description

2-Chloromethyl-6,7-Dimethoxy-3H-Quinazolin-4-One is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive chloromethyl group and quinazolinone scaffold, enabling the construction of complex molecular architectures. This intermediate is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Building block for specialty polymers and advanced organic materials with specific electronic or photonic properties.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	2-Chloromethyl-6,7-Dimethoxy-3H-Quinazolin-4-One
CAS No.	730949-85-6
Molecular Formula	C₁₁H₁₁ClN₂O₃
Molecular Weight	254.67 g/mol
Synonyms	6,7-Dimethoxy-2-(chloromethyl)-3H-quinazolin-4-one; 2-(Chloromethyl)-6,7-dimethoxy-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-(chloromethyl)-6,7-dimethoxy-; 6,7-Dimethoxy-2-chloromethylquinazolin-4(3H)-one; 2-Chloromethyl-6,7-dimethoxyquinazolin-4(3H)-one; CAS 730949-85-6
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-6,7-Dimethoxy-3H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.