Description

Methyl 2-(Chloromethyl)-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily needed by research institutions, custom synthesis houses, and pharmaceutical manufacturers focused on oncology and other specialized drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates, particularly those targeting kinase inhibition.
• API Synthesis: Used in the research and development of Active Pharmaceutical Ingredients (APIs) for potential oncology treatments.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Process Development: Utilized in the scale-up and process optimization stages for new chemical entities (NCEs).

Basic Information

Product Name	Methyl 2-(Chloromethyl)-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylate
CAS No.	730949-68-5
Molecular Formula	C11H9ClN2O3
Molecular Weight	252.65 g/mol
Synonyms	Methyl 2-(chloromethyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylate; 7-Quinazolinecarboxylic acid, 2-(chloromethyl)-3,4-dihydro-4-oxo-, methyl ester; 2-(Chloromethyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid methyl ester; Methyl 2-(chloromethyl)-4-oxo-1,4-dihydroquinazoline-7-carboxylate; CAS 730949-68-5
EINECS	Contact for details

Quality Control

Our Methyl 2-(Chloromethyl)-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.