Description

D-Proline, 3-Propyl-, (3S)-Rel- (9Ci) CAS NO 730923-77-0 is a high-purity, non-natural amino acid derivative belonging to the proline family, characterized by its specific stereochemistry and propyl side chain modification. This compound is a critical chiral building block and intermediate in advanced organic synthesis, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and complex bioactive molecules where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide mimetics and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce conformational constraints or modify the pharmacokinetic properties of therapeutic peptides.
• Asymmetric Catalysis: Acts as a precursor or ligand component in the design of chiral catalysts for enantioselective synthesis.
• Chemical Biology Research: Employed as a molecular probe or building block in studying protein structure, function, and enzyme-substrate interactions.
• Agrochemical Development: Utilized in the synthesis of novel, chiral active ingredients for crop protection products.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	D-Proline, 3-Propyl-, (3S)-Rel- (9Ci)
CAS No.	730923-77-0
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(3S)-3-Propyl-D-proline; (3S)-3-Propyl-D-proline; Rel-(3S)-3-Propyl-D-proline; D-3-Propylproline; (3S)-3-Propyl-D-proline (9CI); 3-Propyl-D-proline; (S)-3-Propyl-D-proline; 730923-77-0
EINECS	Contact for details

Quality Control

Our D-Proline, 3-Propyl-, (3S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing identity, purity (typically >97% by HPLC), and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.