Description

2-(2-Furoyl)-Leu-Ile-Gly-Arg-Leu-Orn-Nh2 is a synthetic peptide derivative, specifically a heptapeptide modified with a furoyl group. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its potential role as a protease inhibitor or a modulator of specific biological pathways. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers engaged in peptide-based drug discovery, enzymology studies, and the development of novel therapeutic agents. The precise sequence and modification offer a valuable tool for investigating protein-protein interactions and designing targeted bioactive molecules.

Application

• Biochemical Research: Used as a reference standard or substrate analog in enzymatic assays and proteomics research.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the discovery and development of novel peptide-based therapeutics.
• Protease Inhibition Studies: Investigated for its potential inhibitory activity against specific proteases like thrombin, trypsin, or furin.
• Cell Signaling Research: Employed in studies exploring intracellular signaling pathways and receptor-ligand interactions.
• Peptide Library Synthesis: Used as a building block in the combinatorial synthesis of focused peptide libraries for high-throughput screening.
• Academic Research: A valuable reagent for universities and research institutes studying peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Product Name	2-(2-Furoyl)-Leu-Ile-Gly-Arg-Leu-Orn-Nh2
CAS No.	729589-58-6
Molecular Formula	C41H70N12O9
Molecular Weight	851.07 g/mol
Synonyms	2-(2-Furoyl)-L-Leucyl-L-Isoleucyl-Glycyl-L-Arginyl-L-Leucyl-L-Ornithinamide; Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2; FI-6; Heptapeptide FI-6; Furoyl Hexapeptide Amide; Protease Inhibitor Peptide; (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2-Furoyl)amino]-4-methylpentanamido]-3-methylpentanamido]acetamido]-5-(diaminomethylideneamino)pentanamido]-4-methylpentanamido]-5-aminopentanamide
EINECS	Contact for details

Quality Control

Our 2-(2-Furoyl)-Leu-Ile-Gly-Arg-Leu-Orn-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, ensuring traceability and compliance with research-grade standards. Our commitment to quality assurance guarantees material integrity for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep frozen. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.