Description

Glutamic Acid, n-[4-[[(2-Amino-6-Pteridinyl)Methyl]Amino]Benzoyl]- is a high-purity, specialized folate derivative with a complex molecular structure. This compound is critical for advanced biochemical research and pharmaceutical development, offering a precise tool for studying folate metabolism and related pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of targeted therapies and diagnostic agents.

Application

• Biochemical Research: A key intermediate and reference standard in folate metabolism studies, enzyme inhibition assays, and receptor binding experiments.
• Pharmaceutical R&D: Serves as a crucial building block for the synthesis of novel antifolate drugs and targeted cancer therapeutics.
• Diagnostic Development: Used in the formulation of assay kits and diagnostic reagents for measuring folate levels and related biomarkers.
• Academic Research: Employed in university and institutional labs for fundamental research in nutrition, cell biology, and metabolic disorders.
• Reference Standard: Provides a high-purity standard for quality control and analytical method validation in pharmaceutical and nutritional supplement manufacturing.

Basic Information

Product Name	Glutamic Acid, n-[4-[[(2-Amino-6-Pteridinyl)Methyl]Amino]Benzoyl]-
CAS No.	728946-34-7
Molecular Formula	C₂₀H₂₁N₉O₅
Molecular Weight	467.44 g/mol
Synonyms	N-[4-[[(2-Amino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid; PT523; Pteroylglutamic acid derivative; Folate analog; Antifolate intermediate; 4-[[(2-Amino-4-oxo-1,4-dihydro-6-pteridinyl)methyl]amino]benzoyl-L-glutamic acid
EINECS	Contact for details

Quality Control

Our Glutamic Acid, n-[4-[[(2-Amino-6-Pteridinyl)Methyl]Amino]Benzoyl]- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant guidelines for laboratory chemicals, and specifications can be aligned with customer requirements for specific research or development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.