Description

4'-Trifluoromethoxy-Biphenyl-4-Ylamine is a high-purity aromatic amine derivative featuring a biphenyl core substituted with a trifluoromethoxy group. This compound is a critical pharmaceutical intermediate and advanced building block for the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the stability imparted by the trifluoromethoxy group.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of advanced liquid crystal compounds for display technologies.
• Organic Electronic Materials: Acts as a core structure in the development of organic semiconductors and charge-transport materials.
• Chemical Research (R&D): A versatile reagent for academic and industrial research in organic synthesis and material science.
• Coordination Chemistry: Potential ligand for metal-organic frameworks (MOFs) and catalytic complexes due to the amine functionality.

Basic Information

Product Name	4'-Trifluoromethoxy-Biphenyl-4-Ylamine
CAS No.	728919-14-0
Molecular Formula	C₁₃H₁₀F₃NO
Molecular Weight	253.22 g/mol
Synonyms	4'-Trifluoromethoxy-[1,1'-biphenyl]-4-amine; 4-Amino-4'-(trifluoromethoxy)biphenyl; 4'-Trifluoromethoxy-4-biphenylamine; [1,1'-Biphenyl]-4-amine, 4'-(trifluoromethoxy)-; 4-(Trifluoromethoxy)biphenyl-4'-amine; Biphenyl-4-ylamine, 4'-trifluoromethoxy-; 4'-Trifluoromethoxybiphenyl-4-amine
EINECS	Contact for details

Quality Control

Our 4'-Trifluoromethoxy-Biphenyl-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.