Description

4-Chloro-2-[[(4-Chlorophenyl)Thio]Methyl]-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and antiviral research domains.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new chemical entities with potential therapeutic effects.
• Kinase Inhibitor Development: Its structural motifs make it a valuable scaffold for the research and development of protein kinase inhibitors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	4-Chloro-2-[[(4-Chlorophenyl)Thio]Methyl]-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine
CAS No.	727718-10-7
Molecular Formula	C17H12Cl2N2S2
Molecular Weight	379.32 g/mol
Synonyms	4-Chloro-2-[(4-chlorophenyl)sulfanylmethyl]-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine; 4-Chloro-2-[[(4-chlorophenyl)thio]methyl]-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine; 727718-10-7; 4-Chloro-2-((4-chlorophenylthio)methyl)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development and commercial projects with quality standards suitable for GMP-grade manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.